Elizabeth Rafferty Tomosynthesis

We needed a better screening tool, and tomosynthesis fills that void.The substantial increase in cancer detection, along with fewer false positive studies, should address any concerns that have lingered over screening this population of women.

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“Radiologists and referring physicians needed an answer for how to screen the roughly half of women with dense breasts, because until now, this patient population was confused and frustrated without a clear path forward,” said , Hologic’s Division President, Breast and Skeletal Health Solutions.

Separately, subgroup data analysis from a previously published retrospective multicenter clinical study (JAMA 2014) supporting breast tomosynthesis as the standard of care in women starting at age 40 has recently been made available.

since 2011, and the newly approved physician labeling is based on clinical studies proving that the exam improves invasive breast cancer detection while reducing unnecessary recalls among women of all breast densities, including those with dense breasts.

Between 40 and 50 percent of women ages 40 to 74 have dense breasts.

This study, “Effect of age on breast cancer screening using tomosynthesis in combination with digital mammography,” led by , MD, was published online in advance of print in Breast Cancer Research and Treatment and analyzed the performance of tomosynthesis in specific age groups.

The study showed that with the addition of tomosynthesis to digital mammography, detection rates for invasive cancer increased significantly for women ages 40 to 69.We will also present the benefits of DBT in screening, diagnostic workup, and image-guided biopsy. Note straightening of adjacent tissue, which is most obvious clue that subtle mass is present (circle).Corresponding mass was seen on ultrasound (not shown), and ultrasound-guided core needle biopsy revealed well-differentiated invasive ductal carcinoma, estrogen-receptor positive, progesterone receptor positive, and Erb B-2 (also known as HER2/neu)-negative at both sites.Tomosynthesis (also called 3-D mammography) is a new and a better way to screen for breast cancer, and is not associated with increased radiation exposure.Women with dense breasts have an increased risk of breast cancer, and tomosynthesis helps unmask cancers hidden by the overlapping tissue.One reason for the lack of clear improvement in performance with digital mammography is that superimposition of normal tissue can obscure masses or malignancy when two-dimensional imaging is used on three-dimensional structures.Digital technology has led to the development of digital breast tomosynthesis, also called 3-D mammography.World Class CME presents, with the support of an educational grant provided by Hologic, a breast imaging weekend for radiologists.This weekend will feature eight hours of comprehensive hands-on tomosynthesis training at dedicated mammography workstations, as well as many topics facing radiologists today from dense breast regulations to contrast-enhanced mammography.Tomosynthesis has significantly better sensitivity in detecting invasive breast cancers, especially in women with scattered fibroglandular dense breasts, and also helps reduce false positives and the recall rates compared with digital mammography.Tomosynthesis is also a more efficient test, however; the reimbursement by insurers varies between states.